Search of the optimal strategy for refinement of atomic models

نویسندگان

  • P. Afonine
  • A. Urzhumtsev
چکیده

Recently it has been shown (Afonine et al, 2001; Lunin et al., 2002) that the approximation of the maximum likelihood criterion (ML) by a quadratic functional (Lunin & Urzhumtsev, 1999) allows to understand the features of the ML refinement and its advantages with respect to the traditional least-squares (LS) refinement. In this latter, the magnitudes { } S calc F ∈ s s of structure factors calculated from the current atomic model are fitted to the observed structure factor magnitudes { } S obs F ∈ s s by minimisation of ( ) ∑ ∈ − =

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تاریخ انتشار 2002